Disk-shaped compact tension test for fracture analysis on pharmaceutical tablets

Jan. 1, 2023, midnight - by J. Girardot , J.B. Kopp , B. Croquelois , P. Tchoreloff , S. Morel , V. Mazel

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Pharmaceutical tablets must fulfill various requirements, with mechanical strength playing a pivotal role. While the diametral compression test (DCT) is typically employed for evaluation, it can yield unstable failures. By subjecting tablets to load–unload cycles during a DCT, it has been demonstrated that the concept of equivalent linear elastic fracture mechanics, usually applicable to Mode I fracture behavior, can be successfully employed. In this context, the equivalent elastic crack growth resistance, commonly referred to as the resistance curve (R-curve), was determined for the studied material. This analysis unveiled the emergence of a Fracture Process Zone (FPZ), indicative of a quasi-brittle behavior. Furthermore, the cyclic loading applied during the fracture test revealed the presence of a second dissipative mechanism leading to residual crack opening, primarily attributed to friction phenomena within the FPZ.

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$Disk-shaped compact tension test for fracture analysis on pharmaceutical tablets$