Register or Sign in
to unlock feature

you are not authorized to read this article.

Login or register your account to get full access to the tableting technology platform.

Login Register
Please verify your account
Please confirm your email address to validate your registration. Follow the link on email received to verify your email adress.
Re-send verification email
Please complete your registration
You're logged in but you didn't complete your registration.
Complete my registration
Exclusive content

You are not authorized to read this article.

mystylone subscription is required to view this content.

Login Register
Close search
  • Resources
  • Products & Services
    • Compaction Simulators
    • R&D / Process Support
  • Events
  • About
  • Contact Us
  • Sign in
Resources
  1. Home /
  2. Resources /
  3. Newsfeeds /
  4. Bilayer tablet manufacturing - An overview
NEWSFEEDS

Bilayer tablet manufacturing - An overview

March 08, 2024
Remove from favorites
Add to favorites

The text highlights the advantages and challenges of bilayer tablets in pharmaceutical formulations. Bilayer tablets offer controlled delivery of one or more active pharmaceutical ingredients (APIs) within a single tablet, enhancing patient compliance and simplifying medication regimens. Despite these benefits, their novel nature often requires additional formulation activity for commercialization, leading to technical challenges such as tablet delamination and cross-contamination. AbbVie addresses these challenges by investing in technology solutions and customizing equipment for efficient manufacturing. Optimal bilayer tablet formulation involves compressing two formulations into a single tablet while maintaining a physical barrier between them, enabling controlled release profiles. AbbVie's extensive manufacturing capabilities and quality compliance practices ensure safe and high-quality production. The company offers experience in bilayer manufacturing at its facilities in Cork, Ireland; Ludwigshafen, Germany; Lake County, Illinois; and Barceloneta, Puerto Rico, catering to clients' needs for bilayer tablet production.

Read more
Bilayer tablet MEDELPHARM Vom hofe
bilayer bilayer tablet
Contributor(s):
Share Copied!
Comments

No comments posted yet.

Add a comment

Articles you may like

Combination of active ingredients in a single solid form for oral administration: study of formulation and critical compression parameters

Combination of active ingredients in a single solid form for oral administration: study of formulation and critical compression parameters

first_published_at:Jan. 1, 2016, midnight / date_published:Jan. 1, 2016
Papers - 01/01/2016 - by Luca Castrati, Alessandra Rossi, Pierre Tchoreloff
Multilayer tablets have demonstrated efficacy in delivering complex therapeutic solutions, enabling the creation of single-dose forms with multiple active pharmaceutical ingredients (APIs) [16]. In this context, a therapeutic solution for …

20210628_Webinar_Bilayer Bruno

Fundamental investigations on bilayer tablets

first_published_at:July 25, 2022, midnight / date_published:July 25, 2022
Webinar Replays - 25/07/2022 - by Jan Henrik Finke, Bruno Leclercq
Jan Henrik Finke (Doctorate at Technische Universität Braunschweig ), Bruno Leclercq and Delphine Ach-Hubert (MEDELPHARM) share on fundamental investigations on bilayer tablets and effects of process parameters and geometry on …

Tablet_Multilayer_15_HD.original

Exploring bilayer tablet manufacturing

first_published_at:Dec. 1, 2021, midnight / date_published:Dec. 1, 2021
Newsfeeds - 01/12/2021 -
Article published on Pharmaceutical Online that reviews selecting this specific dosage form, manufacturing challenges and how to overcome them, considerations for evaluating a CDMO, and the typical timeframe for scale-up.

More

Related products

Take_off_sensor

Linear ejection device

MEDELPHARM
Introducing the linear ejection device, a versatile accessory designed to seamlessly integrate with the STYL'One …
Accessory_Evo_TabInTab_16

Tab-in-tab device

MEDELPHARM
Tab-in-tab technology (press-coated tablets) showcases multiple advantages including enhanced drug stability, modified release profiles, taste …
Accessory_Evo_gravity_feeder_3

Gravity feeder - STYL'One Evo

MEDELPHARM
The primary function of compaction simulators is to provide reliable data from which information can …
Tapping Feeder - STYL'One Evo 4

Tapping feeder - STYL'One Evo

MEDELPHARM
The primary function of compaction simulators is to provide reliable data from which information can …
Paddle Force Feeder - STYL'One Nano 1

Paddle force feeder - STYL'One Nano

MEDELPHARM
The primary function of compaction simulators is to provide reliable data from which information can …
illustration STYL'One Mist manual lubrication

Manual external lubrication

MEDELPHARM
In development, external lubrication enables the characterization of the compaction behavior of pure APIs or …
Evolution_resize

STYL'One Evo

MEDELPHARM
The STYL’One Evo is a highly versatile compaction simulator designed to support pharmaceutical and nutraceutical …
0.STYLOne_Nano_y66g4Pc_resize

STYL'One Nano

MEDELPHARM
The STYL’One Nano is a compact, benchtop compaction simulator designed for early-stage tablet formulation and …
STYLOne_EVO_OEB3_sans_fond_mod_resize

STYL'One Evo DryCon®

MEDELPHARM
The STYL’One Evo is designed to work under negative pressure and as such, the standard …
STYLONE_EVO_OEB5_transparent_apxkk5N_resize

STYL'One Evo WipCon®

MEDELPHARM
The STYL’One Evo is designed to work under negative pressure and as such, the standard …
laptop laboratory gloves

Looking for additional information?

Let us help you

Contact our experts

GENERAL

  • Terms of service
  • Privacy Policy
  • Cookie Policy
  • About
  • Contact us

Account

  • Login

Follow us on

© 2025 Medelpharm