Examining the effect of spatial distribution of disintegrant particles on tablet disintegratability
first_published_at:Nov. 9, 2023, midnight / date_published:Nov. 9, 2023
Papers
-
09/11/2023 -
by
Audrey Yi Zheng,
Wei Wei Huang,
Li Ying Jolene Poon,
Eunice Siying Wong,
Paul Wan Sia Heng,
Lai Wah Chan
Objective
Typically employed at low concentrations in tablets, superdisintegrants may exhibit an uneven spatial distribution within the tablet, leading to varied disintegration times. This study aimed to explore the impact …