Identifying critical binder attributes to facilitate binder selection for efficient formulation development in a continuous twin screw wet granulation process

March 10, 2021, midnight - by Lise Vandevivere

Remove from favorites

Add to favorites

The investigation focused on evaluating the appropriateness of pharmaceutical binders for continuous twin-screw wet granulation, reflecting the pharmaceutical industry's shift from batch to continuous manufacturing. A comparison was conducted between formulations with high and low solubility, highlighting that the essential attributes guiding binder selection vary depending on the solubility characteristics of the formulation.

Download PDF

Identifying critical binder attributes to facilitate binder selection for efficient formulation development in a continuous twin screw wet granulation process

continuous manufacturing twin-screw granulation pharmaceutical binders granule quality tablet quality granule stylone styl'one evo formulation wet granulation binder